Committed to excellence in research and patient care.

Academic Research Institution

Future Medical Research is a dedicated Academic Research Institution committed to advancing clinical research and prides itself on providing trials that promote the inclusivity of under-represented populations. Our scientific approach originates in the conduct of investigator-initiated research aiming to provide better diagnostic tools as well as a better understanding of the underlying mechanisms responsible for various diseases.

We feel privileged to have the opportunity to share our expertise with the industry and by participating in clinical trials in phase I to phase IV. Our primary goal has and continues to be delivering exceptional care to our study participants and in parallel providing our industry partners with high-quality data.

Our enduring commitment remains centered on providing exceptional care to our study participants and in parallel providing our industry partners with high-quality data. Our team brings decades of experience collaborating with the top 20 pharmaceutical sponsors and CROs, along with partnering with approximately 50 additional sponsor and CRO companies.

Clinic Facilities

Clinic Entrance

Reception

Waiting Room

Exam Room

Nurse Station

Pharmacy

Laboratory

Laboratory with Centrifuge

Laboratory

Laboratory Freezers

Office

Conference Room

Therapeutic Experience

Three decades of clinical research experience in phase I-III including:

  • Alopecia

  • Alzheimer’s Disease

    • MCI

    • Mild

    • Moderate

    • Agitation and Psychosis

  • Asthma

  • Cardiovascular disorders

  • Chronic Obstructive Pulmonary Disease

  • Constipation

  • Diabetes

  • Dyslipidemia

  • Hypertension

  • Irritable Bowel Syndrome

  • Medical devices

  • Menopause

  • Migraine

  • MASH

  • Obesity

  • Osteoarthritis

  • Osteoporosis

  • Pain syndromes

  • Psychiatric disorders

  • Restless legs

  • Rheumatoid arthritis

  • Sleep disorders

  • Smoking cessation

  • Vaccines

Site Capabilities

Our 5000+ square foot clinic is tailored for clinical research programs including, but not limited to, the following:

  • Calibrated height and weight measurements

  • Body mass index (BMI)

  • Ambulatory blood pressure measurements

  • Orthostatic blood pressure measurement

  • ECG including automated QT determination

  • Spirometry

  • Venipuncture including specimen preparation

  • Packaging & shipping

  • Blood smear preparation

  • Pharmacokinetic sampling and storage

  • Urine dipsticks

  • Urine pregnancy testing

Procedures

  • Standard Operating Procedures

  • Central Administration providing a one-stop entry with turn-around timelines from 1 to 3 business days - Review of Confidentiality Agreements

    • Scientific review of synopsis/study protocol

    • Feasibility process

    • Budgeting review

    • Contracting review

Administration

  • GCP/ICH certification

  • HIPAA certification

  • Blood Bourne Pathogen certification

  • Biomedical Waste Management certification

  • HazMat certification

  • Personal Protective Equipment certification

  • IATA certification

  • Various e-CRF programs

  • Various IVRS systems

  • Various log pad/paper/IVRS patient diaries

Trainings

  • CTMS Clinical Trial Management System (CTMS)

  • Microsoft Office 365

    • Microsoft Word, Excel, Teams, PowerPoint, Publisher

  • Adobe Creative Suite

Facility Software

  • Monitoring rooms

  • Procedure and treatment rooms

    • Injections

    • Infusions

  • Dedicated Pharmacies in two separate locations with restricted access and suitable to manage blinded and unblinded medication

    • Temperature controlled 24/7

    • Refrigerators with 24/7 Temperature Control

    • Individually lockable Pharmacy Cabinets

  • Dedicated Laboratory with restricted access

    • Dry Ice

    • Refrigerators with 24/7 Temperature Control

    • Freezers

      • Minus 20 Degrees Celsius with 24/7 Temperature Control

      • Minus 80 Degrees Celsius with 24/7 Temperature Control

    • Centrifuges

      • Ambient and refrigerated

    • Class II, Type A2 Biosafety Cabinet

    • PBMC Processing

    • ECG

Facility Hardware

  • Local certified lab

  • Local Imaging

    • X-ray

    • CT

    • MRI (1.5 and 3 Tesla)

    • DXA

Local Accessibility

Ratings Scale Expertise

  • Alzheimer’s Disease Assessment Scale - Cognitive (ADAS-Cog)

  • Agitation-Calmness Evaluation Scale (ACES)

  • Clinical Dementia Rating (CDR) - Global Score

  • Clinical Dementia Rating - Sum of Boxes (CDR-SB)

  • Clinical Global Impression (CGI) Scale

    • CGI-Severity (CGI-S)

    • CGI-Improvement (CGI-I)

  • Cohen-Mansfield Agitation Inventory (CMAI)

  • Columbia-Suicide Severity Rating Scale (C-SSRS)

  • EuroQol-5 Dimensions-5 Level (EQ-5D-5L Proxy)

  • Mini-Mental Status Examination (MMSE)

  • Neuropsychiatric Inventory - Clinician Rating Scale (NPI-C)

  • Neuropsychiatric Inventory - 12-item version (NPl-12)

  • Positive and Negative Syndrome Scale - Excited Component (PANSS-EC/PEC)

  • Pittsburg Agitation Scale (PAS)

  • Positive and Negative Syndrome Scale (PEC)

Scientific Publications Peer Reviewed

  • Dennison EM, Cooper C, Inskip H; SEKOIA Study Group. Novel Approach to Estimate Osteoarthritis Progression: Use of the Reliable Change Index in the Evaluation of Joint Space Loss. Arthritis Care Res (Hoboken). 2019 Feb;71(2):300-307. doi: 10.1002/acr.23596.

  • Edwards MH, Parsons C, Bruyère O, Petit Dop F, Chapurlat R, Roemer FW, Guermazi A, Zaim S, Genant H, Reginster JY, Dennison EM, Cooper C; SEKOIA Study Group. High Kellgren-Lawrence Grade and Bone Marrow Lesions Predict Worsening Rates of Radiographic Joint Space Narrowing; The SEKOIA Study. J Rheumatol. 2016 Mar;43(3):657-65. doi: 10.3899/jrheum.150053.

  • Arendt-Nielsen L, Egsgaard LL, Petersen KK, Eskehave TN, Graven-Nielsen T, Hoeck HC, Simonsen O. A Mechanism-based pain sensitivity index to characterize knee osteoarthritis patients with different disease stages and pain levels. Eur J Pain. 2015;19:1406-17.

  • Andersen JR, Byrjalsen I, Bihlet A, Kalakou F, Hoeck HC, Hansen G, Hansen HB, Karsdal MA, Riis BJ. Impact of Source Data Verification on data quality in clinical trials: An empirical post-hoc analysis of three phase 3 randomised clinical trials. Br J Clin Pharmacol. 2015 Apr;79(4):660-8. doi: 10.1111/bcp.12531.

  • Egsgaard LL, Eskehave TN, Bay-Jensen AC, Hoeck HC, Arendt-Nielsen L. Identifying specific profiles in patients with different degrees of painful knee osteoarthritis based on serological biochemical and mechanistic pain biomarkers: a diagnostic approach based on cluster analysis. Pain 2015 Jan;156(1):96-107. doi: 10.1016/j.pain.0000000000000011.

  • Nygaard B, Frandsen NE, Brandi L, Rasmussen K, Oestergaard OV, Oedum L, Hoeck HC, Hansen D. Effects of high doses of cholecalciferol in normal subjects: a randomized double-blinded, placebo-controlled trial. PLoS One. 2014 Aug 28;9(8):e102965. doi: 10.1371 / journal.pone.0102965. eCollection 2014.

  • Arendt-Nielsen L, Eskehave TN, Egsgaard LL, Petersen KK, Graven-Nielsen T, Hoeck HC, Simonsen O, Siebuhr AS, Karsdal M, Bay-Jensen AC. Association Between Experimental Pain Biomarkers and Serological Markers in Patients With Different Degree of Painful Knee Osteoarthritis. Arthritis Rheumatol. 2014 Aug 28. doi: 10.1002/art.38856.

  • He Y, Siebuhr AS, Brandt-Hansen NU, Wang J, Su D, Zheng Q, Simonsen O, Petersen KK, Arendt-Nielsen L, Eskehave T, Hoeck HC, Karsdal MA, Bay-Jensen AC. Type X collagen levels are elevated in serum from human osteoarthritis patients and associated with biomarkers of cartilage degradation and inflammation. BMC Musculoskelet Disord. 2014 Sep 22;15:309. doi: 10.1186/1471-2474-15-309.

  • Siebuhr AS, Petersen KK, Arendt-Nielsen L, Egsgaard LL, Eskehave T, Christiansen C, Simonsen O, Hoeck HC, Karsdal MA, Bay-Jensen AC. Identification and characterisation of osteoarthritis patients with inflammation derived tissue turnover. Osteoarthritis Cartilage. 2013;Nov pii: S1063-4584(13)01003-0. doi: 10.1016/j.joca.2013.10.020.

  • Jakobsen, L.A., Jensen, A., Larsen, L.E., Sørensen, M.R., Hoeck, HC, Arendt-Nielsen, L., Gazerani, P. Effect of cutaneous blood low on absorption of insulin: A methodological study in healthy male volunteers. Int J Physiol Pathophysiol Pharmacol. 2011;3:257-65.

    Arendt-Nielsen L., Hoeck HC. Optimizing the Early Phase Development of New Analgesics by Human Pain Biomarkers. Expert Rev Neurother. 2011 Nov;11:1631-51.

  • McClung MR, Boonen S, Törring O, Roux C, Rizzoli R, Bone HG, Benhamou CL, Lems WF, Minisola S, Halse J, Hoeck HC, Eastell R, Wang A, Siddhanti S, Cummings SR. Effect of denosumab treatment on the risk of fractures in subgroups of women with postmenopausal osteoporosis. J Bone Miner Res. 2012 Jan;27(1):211-8.

  • Item descriptionSilverman SL, Chines AA, Kendler DL, Kung AW, Teglbjærg CS, Felsenberg D, Mairon N, Constantine GD, Adachi JD; Bazedoxifene Study Group. Sustained efficacy and safety of bazedoxifene in preventing fractures in postmenopausal women with osteoporosis: results of a 5-year, randomized, placebo-controlled study. Osteoporos Int. 2012 Jan;23(1):351-63.

  • Chandran M, Hoeck HC, Wong HC, Zhang RF, Dimai HP. Vitamin D status and its relationship with bone mineral density and parathyroid hormone in South-East Asian adults with low bone density. Endocr Pract. 2010;Nov 1:1-24.

  • Item descriptionArendt-Nielsen, L., Hoeck, HC, Karsdal, M. A. & Christiansen, C. Role of calcitonin in management of musculoskeletal pain. Rheumatology Reports 2009:1:39-42.

  • Li B, Byrjalsen I, Glendenning P, Henriksen DB, Hoeck HC, Taranto M, Vasikaran S, Fraser WD, Christiansen C, Qvist P. Selective monitoring of vitamin D(2) and D(3) supplementation with a highly specific 25-hydroxyvitamin D(3) immunoassay with negligible cross-reactivity to 25-hydroxyvitamin D(2). Clin Chim Acta. 2009;404:144-148.

  • Ovesen J, Møller-Madsen B, Nielsen PT, Christensen PH, Simonsen O, Hoeck HC, Laursen MB, Thomsen JS. Differences in zinc status between patients with osteoarthritis and osteoporosis. J Trace Elem Med Biol. 2009;23(1):1-8.

  • Item descriptionHoeck HC, Li B, Qvist P. Changes in 25-Hydroxyvitamin D3 to oral treatment with vitamin D3 in postmenopausal females with osteoporosis. Osteoporos Int. 2009;20:1329-1335.

  • Laessoe U, Hoeck HC, Simonsen O, Voigt M. Residual attentional capacity amongst young and elderly during dual and triple task walking. Hum Mov Sci. 2008;27:496-512.

  • Miller PD, Christiansen C, Hoeck HC, Kendler DL, Lewiecki EM, Woodson G, Levine AB, Chines AA, Constantine G, Delmas PD. Effects of Bazedoxifene on Bone Mineral Density and Turnover in Postmenopausal Women: 2-Year Results of a Randomized, Double-Blind, Placebo- and Active-Controlled Study. J Bone Miner Res 2008;23:525-35.

  • Thomsen JS, Nielsen PT, Christensen PH, Simonsen O, Hoeck HC, Laursen MB, Møller-Madsen B, Ovesen J. Differences in zinc status, bone turnover and femoral head bone density and biomechanical properties between patients with osteoarthritis and osteoporosis. J Musculoskelet Neuronal Interact. 2008;8:22.

  • Hoeck HC. Behandling og kontrol af D-vitamin mangel i praksis. NOLK 2008;1:14-17

  • Laessoe U, Hoeck HC, Simonsen O, Sinkjaer T, Voigt M. Fall risk in an active elderly population – can it be assessed? Journal of Negative Results in BioMedicine 2007,6:2. DOI: 10.1186/1477-5751-6-2.

  • Vestergaard P, Jorgensen JO, Hagen C, Hoeck HC, Laurberg P, Rejnmark L, Brixen K, Weeke J, Andersen M, Conceicao FL, Nielsen TL, Mosekilde L. Fracture risk is increased in patients with GH deficiency or untreated prolactinomas--a case-control study. Clin Endocrinol (Oxf). 2002 Feb;56(2):159-67.

  • Vestergaard P, Rejnmark L, Weeke J, Hoeck HC, Nielsen HK, Rungby J, Laurberg P, Mosekilde L. Smoking as a risk factor for Graves’ disease, toxic nodular goiter, and autoimmune hypothyroidism. Thyroid. 2002 Jan;12(1):69-75.

  • Sneppen SB, Hoeck HC, Kollerup G, Sorensen OH, Laurberg P, Feldt-Rasmussen U. Bone mineral content and bone metabolism during physiological GH treatment in GH-deficient adults--an 18-month randomised, placebo-controlled, double blinded trial. Eur J Endocrinol. 2002 Feb;146(2):187-95.

  • Vestergaard P, Lindholm J, Jorgensen JO, Hagen C, Hoeck HC, Laurberg P, Rejnmark L, Brixen K, Kristensen LO, Feldt-Rasmussen U, Mosekilde L. Increased risk of osteoporotic fractures in patients with Cushing’s syndrome. Eur J Endocrinol. 2002 Jan;146(1):51-6.

  • Vestergaard P, Weeke J, Hoeck HC, Nielsen HK, Rungby J, Rejnmark L, Laurberg P, Mosekilde L. Fractures in patients with primary idiopathic hypothyroidism. Thyroid. 2000 Apr;10(4):335-40.

  • Hoeck HC, Vestergaard P, Jakobsen PE, Falhof J, Laurberg P. Diagnosis of growth hormone (GH) deficiency in adults with hypothalamic-pituitary disorders: comparison of test results using pyridostigmine plus GH-releasing hormone (GHRH), clonidine plus GHRH, and insulin-induced hypoglycemia as GH secretagogues. J Clin Endocrinol Metab. 2000 Apr;85(4):1467-72.

  • Hoeck HC, Jakobsen PE, Vestergaard P, Falhof J, Laurberg P. Differences in reproducibility and peak growth hormone responses to repeated testing with various stimulators in healthy adults. Growth Horm IGF Res. 1999 Feb;9(1):18-24.

  • Vestergaard P, Hoeck HC, Jakobsen PE, Laurberg P. Reproducibility of growth hormone and cortisol responses to the insulin tolerance test and the short ACTH test in normal adults. Horm Metab Res. 1997 Mar;29(3):106-10.

  • Item descriptionJakobsen PE, Hoeck HC. Ambulant elektrokardiografi i en klinisk kemisk afdeling. NOLK 1995.

  • Hoeck HC, Vestergaard P, Jakobsen PE, Laurberg P. Test of growth hormone secretion in adults: poor reproducibility of the insulin tolerance test. Eur J Endocrinol. 1995 Sep;133(3):305-12.

  • Laurberg P, Jakobsen PE, Hoeck HC, Vestergaard P. Growth hormone and thyroid function: is secondary thyroid failure underdiagnosed in growth hormone deficient patients? Thyroidology. 1994 Dec;6(3):73-9. Review.

  • Laurberg P, Hoeck HC, Jakobsen PE, Vestergaard P. Secondary thyroid failure may be underdiagnosed and undertreated in growth hormone (GH) deficient adults. Thyroid 1994;4(Suppl 1):S-21.

  • Kristensen M, Hoeck HC. [Abnormal flora in the small intestine. Diagnostic evaluation of the H2 breath test] Ugeskr Laeger. 1994 Dec 12;156(50):7530-3. [Danish].

  • Hoeck HC, Bang F, Laurberg P. Impaired growth hormone secretion in patients operated for pituitary adenomas. Growth Regul. 1994 Jun;4(2):63-7.

  • Hoeck HC, Laurberg G, Laurberg P: Hypercalcaemic crisis after excessive topical use of a vitamin D derivative. J Intern Med. 1994 Mar;235(3):281-2.

  • Godballe C, Hoeck HC, Sørensen JA. [Transient abnormal Q-waves] Ugeskr Laeger. 1990 Jan 8;152(2):92-4. Danish.

For more details please visit: https://pubmed.ncbi.nlm.nih.gov/

Partner Sites

Future Medical Research collaborates closely with Research Works, situated in New Orleans and San Juan, Puerto Rico.